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Quantitative single breath-hold renal arterial spin labeling imaging at 7T
| Content Provider | Scilit |
|---|---|
| Author | Li, Xiufeng Auerbach, Edward J. de Moortele, Pierre-Francois Van Ugurbil, Kamil Metzger, Gregory J. |
| Copyright Year | 2017 |
| Description | Journal: Magnetic Resonance in Medicine To evaluate the feasibility of quantitative single breath-hold renal arterial spin labeling (ASL) imaging at 7T. A single-shot fast spin echo FAIR (flow-sensitive alternating inversion recovery) method was used to perform two studies. First, a multi-delay perfusion study was performed to estimate the spin labeling temporal bolus width achievable with a local transceiver array coil at 7T. Second, with a conservatively defined bolus width, a quantitative perfusion study was performed using the single subtraction approach. To address issues of B1+ inhomogeneity/efficiency and excessive short-term specific absorption rates, various strategies were used, such as dynamic radiofrequency shimming and optimization. A conservative temporal bolus width of 600 ms determined from the multi-delay study was applied for single-subtraction imaging to measure the renal blood flow in the cortex and medulla: 303 ± 31.8 and 91.3 ± 15.2 (mL/100 g/min), respectively. The estimated spatial and temporal signal-to-noise ratios of renal perfusion measurements were 3.8 ± 0.7 and 2.4 ± 0.6 for the cortex, and 2.2 ± 0.6 and 1.4 ± 0.2 for the medulla. With proper management of field strength specific challenges, quantitative renal ASL imaging can be achieved at 7T within a single breath-hold. Magn Reson Med 79:815-825, 2018. © 2017 International Society for Magnetic Resonance in Medicine. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680158/pdf |
| Ending Page | 825 |
| Page Count | 11 |
| Starting Page | 815 |
| e-ISSN | 15222594 |
| DOI | 10.1002/mrm.26742 |
| Journal | Magnetic Resonance in Medicine |
| Issue Number | 2 |
| Volume Number | 79 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2017-05-09 |
| Access Restriction | Open |
| Subject Keyword | Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Arterial Spin Labeling (asl) Magnetic Resonance Imaging (mri) Renal Perfusion Or Renal Blood Flow (rbf) Ultrahigh Field (uhf) |
| Content Type | Text |
| Resource Type | Article |