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Reduction in late-onset sepsis on relocating a neonatal intensive care nursery
| Content Provider | Scilit |
|---|---|
| Author | Jones, Alicia Rose Kuschel, Carl Jacobs, Susan Doyle, Lex W. |
| Copyright Year | 2012 |
| Description | Journal: Journal of Paediatrics and Child Health The aims of this study were to compare rates of late-onset sepsis (LOS) in very preterm or very low birthweight infants before and after relocation to a new nursery and to determine risk factors for LOS. The study was undertaken at The Royal Women's Hospital, Melbourne, which relocated to a new site in June 2008. Infants with birthweight 48 h after birth and was categorised as definite, probable, uncertain or no sepsis. Overall, 117 infants had 218 septic episodes. The proportion of infants with clinical LOS decreased from 29.5% in 2007 to 22.4% in 2008 after the relocation, although this was not statistically significant. There was a significant (P < 0.05) reduction in the severity (definite LOS = most severe) of sepsis in 2008 compared with 2007, and in rates of coagulase-negative staphylococcal LOS. Significant risk factors for LOS were: lower birthweight (g; mean -351, 95% confidence interval (CI) -446, -256); lower gestational age (weeks; mean -2.3, 95% CI -2.8, -1.7) and presence of a percutaneous inserted central catheter (odds ratio (OR) 2.56, 95% CI 1.03, 6.67). There was a significant reduction in the severity of LOS in very preterm and/or very low birthweight infants that correlated with the relocation from the old to new nursery. Smaller and more immature infants with percutaneous central catheters were more at risk. |
| Ending Page | 895 |
| Starting Page | 891 |
| ISSN | 2573508X |
| e-ISSN | 14401754 |
| DOI | 10.1111/j.1440-1754.2012.02524.x |
| Journal | Journal of Paediatrics and Child Health |
| Issue Number | 10 |
| Volume Number | 48 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2012-08-16 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Paediatrics and Child Health Intensive Care Unit Late‐onset Sepsis |
| Content Type | Text |
| Resource Type | Article |
