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Multipathway sequences for MR thermometry

Content Provider	Scilit
Author	Madore, Bruno Panych, Lawrence P. Mei, Chang-Sheng Yuan, Jing Chu, Renxin
Copyright Year	2011
Description	Journal: Magnetic Resonance in Medicine MR-based thermometry is a valuable adjunct to thermal ablation therapies as it helps to determine when lethal doses are reached at the target and whether surrounding tissues are safe from damage. When the targeted lesion is mobile, MR data can further be used for motion-tracking purposes. The present work introduces pulse sequence modifications that enable significant improvements in terms of both temperature-to-noise-ratio properties and target-tracking abilities. Instead of sampling a single magnetization pathway as in typical MR thermometry sequences, the pulse-sequence design introduced here involves sampling at least one additional pathway. Image reconstruction changes associated with the proposed sampling scheme are also described. The method was implemented on two commonly used MR thermometry sequences: the gradient-echo and the interleaved echo-planar imaging sequences. Data from the extra pathway enabled temperature-to-noise-ratio improvements by up to 35%, without increasing scan time. Potentially of greater significance is that the sampled pathways featured very different contrast for blood vessels, facilitating their detection and use as internal landmarks for tracking purposes. Through improved temperature-to-noise-ratio and lesion-tracking abilities, the proposed pulse-sequence design may facilitate the use of MR-monitored thermal ablations as an effective treatment option even in mobile organs such as the liver and kidneys.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134596/pdf
Ending Page	668
Page Count	11
Starting Page	658
e-ISSN	15222594
DOI	10.1002/mrm.22844
Journal	Magnetic Resonance in Medicine
Issue Number	3
Volume Number	66
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2011-03-09
Access Restriction	Open
Subject Keyword	Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Mr Thermometry Prf Imaging Image Guided Therapy
Content Type	Text
Resource Type	Article

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