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Flow-induced signal misallocation artifacts in two-point fat-water chemical shift MRI
| Content Provider | Scilit |
|---|---|
| Author | Rahimi, Mahdi Salmani Holmes, James H. Wang, Kang Reeder, Scott B. Korosec, Frank R. |
| Copyright Year | 2014 |
| Description | Journal: Magnetic Resonance in Medicine Two-point fat-water separation methods are increasingly being used for chest and abdominal MRI and have recently been introduced for use in MR angiography of the lower extremities. With these methods, flowing spins can accumulate unintended phase shifts between the echo times. The purpose of this study is to demonstrate that these phase shifts can lead to inaccurate signals in the water and fat images. In vitro experiments were conducted at 1.5T and 3.0T using a stenosis-mimicking phantom and a computer-controlled pump to image a range of physiologically relevant velocities. In the phantom images acquired using bipolar readout gradients, fat-water signal inaccuracies were visible in regions of flow, with increasing severity as the flow rate was increased. Additionally, similar effects were observed in regions of high flow in clinical chest and liver exams. In the phantom images, the effect was eliminated by using a dual-pass method without bipolar readout gradients. When using fat-water separation methods with bipolar readout gradients, phase shifts caused by the motion of spins can lead to signal inaccuracies in the fat and water images. These artifacts can be mitigated by using approaches that do not use bipolar readout gradients. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363294/pdf |
| Ending Page | 1931 |
| Page Count | 6 |
| Starting Page | 1926 |
| e-ISSN | 15222594 |
| DOI | 10.1002/mrm.25315 |
| Journal | Magnetic Resonance in Medicine |
| Issue Number | 5 |
| Volume Number | 73 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2014-06-09 |
| Access Restriction | Open |
| Subject Keyword | Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Chemical Shift Separation Flow Artifacts Nonsubtractive Mra Two-point Fat-water Separation |
| Content Type | Text |
| Resource Type | Article |