NDLI: Treatment of recalcitrant pustular psoriasis with infliximab: effective reduction of chemokine expression

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Treatment of recalcitrant pustular psoriasis with infliximab: effective reduction of chemokine expression

Content Provider	Scilit
Author	Benoit, S. Toksoy, A. Brocker, E-B. Gillitzer, R. Goebeler, M.
Copyright Year	2004
Description	Journal: British Journal of Dermatology A 74-year-old Caucasian man with severe long-standing Palmoplantar pustular psoriasis (PPP) was treated with systemic therapy with efalizumab. Considerable improvement of PPP was observed after only 4 weeks of treatment and a complete recovery of daily activities was obtained after three months of therapy. A month later a sudden importantud ud absence of side effects; adult; aged; blood testis barrier; case report; drug withdrawal; human; labud reappearance of pustules wereud noted. Systemic acitretin at an initial dose of 0.5 mg/kg/dud was started while continuing efalizumab. After 15 days anud almost complete disappearance of pustular lesions was reobserved. The dermatosis relapsed after suspension of the retinoid, despite ongoing efalizumab
Ending Page	1012
Starting Page	1009
ISSN	2573508X
e-ISSN	13652133
DOI	10.1111/j.1365-2133.2004.05960.x
Journal	British Journal of Dermatology
Issue Number	5
Volume Number	150
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2004-05-01
Access Restriction	Open
Subject Keyword	Journal: British Journal of Dermatology Growth‐related Oncogene‐α Monocyte Chemoattractant Protein‐1 Pustular Psoriasis Tumour Necrosis Factor‐α
Content Type	Text
Resource Type	Article

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