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Practical Utility of the Revised European-American Classification of Lymphoid Neoplasms for Japanese Non-Hodgkin's Lymphomas

Content Provider	Scilit
Author	Izumo, Toshiyuki Maseki, Nobuo Mori, Shigeo Tsuchiya, Eiju
Copyright Year	2000
Description	Journal: Japanese Journal of Cancer Research A clinicopathological study of 515 non‐Hodgkin's lymphoma (NHL) cases was performed using the revised European‐American classification of lymphoid neoplasms (REAL classification) in an HTLV1‐nonendemic area of Japan. The following characteristics were revealed: 1) frequency of extranodal lymphomas was high (59%) with 79% B‐cell lymphomas in this series, while the overall ratio of B:T/NK lineage was 3.7:1; 2) the most common type was the diffuse large B‐cell lymphoma (46%), follicle center lymphomas occurred at an incidence lower (15%) than that in European and American populations, and marginal zone B‐cell lymphomas accounted for as much as 12%; 3) peripheral T‐cell lymphomas were common (19%), with the unspecified type predominant (11%), while adult T‐cell lymphomas were present at a level equivalent to that among European and American patients (1%). Clear segregation of survival curves was rated according to cell lineage and B‐cell lymphomas had a better prognosis than T/NK‐cell lymphomas. Furthermore, new subtypes in the REAL classification, such as marginal zone B‐cell and mantle cell lymphomas, exhibited distinct curves. Taken altogether, the REAL classification demonstrated advantages for assessment of Japanese NHL cases.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926366/pdf http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.2000.tb00952.x/pdf
Ending Page	360
Page Count	10
Starting Page	351
ISSN	09105050
DOI	10.1111/j.1349-7006.2000.tb00952.x
Journal	Japanese Journal of Cancer Research
Issue Number	3
Volume Number	91
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2000-03-01
Access Restriction	Open
Subject Keyword	Journal: Japanese Journal of Cancer Research Real Classification Non‐hodgkin's Lymphoma
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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