NDLI: Specificity of Ethylcholine Mustard Aziridinium as an Irreversible Inhibitor of Choline Transport in Cholinergic and Noncholinergic Tissue

Content Provider	Scilit
Author	Uney, J. B. Marchbanks, R. M.
Copyright Year	1987
Description	Journal: Journal of Neurochemistry The sensitivity of choline transport to inhibition by ethylcholine mustard aziridinium (ECMA) was studied in several tissues. Choline transport was found to be inhibited irreversibly by ECMA in guinea pig and rat synaptosomes but not inhibited in erythrocytes or kidney slices. If this finding can be extended to other tissues ECMA sensitivity may provide a simple criterion for identifying the choline carrier associated with cholinergic tissue.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.1987.tb05722.x/pdf
Ending Page	1676
Page Count	4
Starting Page	1673
e-ISSN	14714159
DOI	10.1111/j.1471-4159.1987.tb05722.x
Journal	Journal of Neurochemistry
Issue Number	6
Volume Number	48
Language	English
Publisher	Wiley-Blackwell
Publisher Date	1987-06-01
Access Restriction	Open
Subject Keyword	Journal: Journal of Neurochemistry Ethylcholine Mustard Aziridinium Choline Transport
Content Type	Text
Resource Type	Article

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Specificity of Ethylcholine Mustard Aziridinium as an Irreversible Inhibitor of Choline Transport in Cholinergic and Noncholinergic Tissue