NDLI: Single-shot magnetic resonance spectroscopic imaging with partial parallel imaging

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Single-shot magnetic resonance spectroscopic imaging with partial parallel imaging

Content Provider	Scilit
Author	Posse, Stefan Otazo, Ricardo Tsai, Shang-Yueh Yoshimoto, Akio Ernesto Lin, Fa-Hsuan
Copyright Year	2008
Description	Journal: Magnetic Resonance in Medicine A magnetic resonance spectroscopic imaging (MRSI) pulse sequence based on proton-echo-planar-spectroscopic-imaging (PEPSI) is introduced that measures two-dimensional metabolite maps in a single excitation. Echo-planar spatial-spectral encoding was combined with interleaved phase encoding and parallel imaging using SENSE to reconstruct absorption mode spectra. The symmetrical k-space trajectory compensates phase errors due to convolution of spatial and spectral encoding. Single-shot MRSI at short TE was evaluated in phantoms and in vivo on a 3-T whole-body scanner equipped with a 12-channel array coil. Four-step interleaved phase encoding and fourfold SENSE acceleration were used to encode a 16 x 16 spatial matrix with a 390-Hz spectral width. Comparison with conventional PEPSI and PEPSI with fourfold SENSE acceleration demonstrated comparable sensitivity per unit time when taking into account g-factor-related noise increases and differences in sampling efficiency. LCModel fitting enabled quantification of inositol, choline, creatine, and N-acetyl-aspartate (NAA) in vivo with concentration values in the ranges measured with conventional PEPSI and SENSE-accelerated PEPSI. Cramer-Rao lower bounds were comparable to those obtained with conventional SENSE-accelerated PEPSI at the same voxel size and measurement time. This single-shot MRSI method is therefore suitable for applications that require high temporal resolution to monitor temporal dynamics or to reduce sensitivity to tissue movement.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827332/pdf
Ending Page	547
Page Count	7
Starting Page	541
e-ISSN	15222594
DOI	10.1002/mrm.21855
Journal	Magnetic Resonance in Medicine
Issue Number	3
Volume Number	61
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2008-12-18
Access Restriction	Open
Subject Keyword	Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Magnetic Resonance Spectroscopic Imaging Single-shot Encoding Proton Echo Planar Spectroscopic Imaging Parallel Imaging Spectral Quantification
Content Type	Text
Resource Type	Article

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