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Ovulation induction in polycystic ovary syndrome
| Content Provider | Scilit |
|---|---|
| Author | Tanbo, Tom Mellembakken, Jan Roar Bjercke, Sverre Ring, Eva Åbyholm, Thomas Fedorcsak, Peter |
| Copyright Year | 2018 |
| Description | Journal: Acta Obstetricia et Gynecologica Scandinavica The objective of this narrative review is to suggest a rational order of treatment choices in anovulatory women with polycystic ovary syndrome (PCOS), for whom a multitude of treatment options exist. In obese/overweight PCOS patients the importance of weight reduction should be stressed. Inositol, a dietary supplement with a documented effect on ovulation and without side effects in the doses recommended, may be suggested. Additional first line medical alternatives include insulin sensitizers, selective estrogen receptor modulators and aromatase inhibitors. Of these, the aromatase inhibitor letrozole and the combination of clomiphene citrate and metformin have the highest rates of ovulation and live birth. Second line treatments are ovarian electrocautery and low‐dose follicle stimulating hormone stimulation. Controlled ovarian stimulation with in vitro fertilization, should be considered the last option since it carries a significant risk of ovarian hyperstimulation syndrome in patients with PCOS. This article is protected by copyright. All rights reserved. |
| Ending Page | 1167 |
| Starting Page | 1162 |
| ISSN | 00221295 |
| e-ISSN | 16000412 |
| DOI | 10.1111/aogs.13395 |
| Journal | Acta Obstetricia et Gynecologica Scandinavica |
| Issue Number | 10 |
| Volume Number | 97 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2018-10-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Obstetricia et Gynecologica Scandinavica Obstetrics and Gynecology Polycystic Ovary Syndrome Aromatase Inhibitors Selective Estrogen Modulators Follicle Stimulating Hormone in Vitro Fertilization |
| Content Type | Text |
| Resource Type | Article |
| Subject | Obstetrics and Gynecology |
