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Outcomes of monoamniotic twin pregnancies managed primarily in outpatient care-a Danish multicenter study
| Content Provider | Scilit |
|---|---|
| Author | Madsen, Caroline Søgaard, Kirsten Zingenberg, Helle Jørgensen, Finn Stener Rosbach, Hanne Hoseth, Eva Pedersen, Lars Henning Petersen, Olav Bjørn |
| Copyright Year | 2018 |
| Description | Journal: Acta Obstetricia et Gynecologica Scandinavica Introduction Monoamniotic twin pregnancies are high‐risk pregnancies, and management by inpatient or frequent outpatient care is recommended. We report the outcomes of a national cohort of monoamniotic twin pregnancies managed primarily as outpatients Material and methods We analyzed prospectively recorded data from the Danish Fetal Medicine Database, local databases, and medical records of all monoamniotic twin pregnancies diagnosed at the first trimester scan or later, and managed at the six major fetal medicine centers in Denmark over a 10 year period Results Sixty‐one monoamniotic twin pregnancies were included. Thirteen pregnancies were terminated early. Of the remaining 48 pregnancies with a normal first trimester scan, there were 36 fetal losses (25 spontaneous miscarriages 22 weeks) and 60 live‐born children (62.5%), all of whom were delivered by cesarean delivery at a median gestational age of 33+0 weeks. Three children had minor malformations and there was one pregnancy with twin‐to‐twin‐transfusion‐syndrome. After 26+0 weeks, 78.8% were managed as outpatients. Intrauterine death occurred in 3.8% of outpatients and in 28.6% of inpatients (admitted due to complications). At weeks 32, 33, and 34, the prospective risk of intrauterine death was 6.9%, 4.2%, and 5.9%, respectively Conclusion In this nationwide, unselected population, only 62.5% of fetuses with a normal first trimester scan were born alive. In contrast, the mortality was 3.8% after 26 weeks among the 78.8% of the cohort that was managed as outpatients. More knowledge is still needed to predict which pregnancies are at the highest risk of intrauterine death. This article is protected by copyright. All rights reserved. |
| Ending Page | 486 |
| Starting Page | 479 |
| ISSN | 00221295 |
| e-ISSN | 16000412 |
| DOI | 10.1111/aogs.13509 |
| Journal | Acta Obstetricia et Gynecologica Scandinavica |
| Issue Number | 4 |
| Volume Number | 98 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2018-11-25 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Obstetricia et Gynecologica Scandinavica Obstetrics and Gynecology Monoamniotic Twin Pregnancy Twin‐to‐twin‐transfusion Syndrome Intrauterine Fetal Death |
| Content Type | Text |
| Resource Type | Article |
| Subject | Obstetrics and Gynecology |
