NDLI: Robust diffusion tensor imaging by spatiotemporal encoding: Principles and in vivo demonstrations

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Robust diffusion tensor imaging by spatiotemporal encoding: Principles and in vivo demonstrations

Content Provider	Scilit
Author	Solomon, Eddy Liberman, Gilad Nissan, Noam Frydman, Lucio
Copyright Year	2016
Description	Journal: Magnetic Resonance in Medicine Evaluate the usefulness of single-shot and of interleaved spatiotemporally encoded (SPEN) methods to perform diffusion tensor imaging (DTI) under various preclinical and clinical settings. A formalism for analyzing SPEN DTI data is presented, tailored to account for the spatially dependent b-matrix weightings introduced by the sequence's use of swept pulses acting while in the presence of field gradients. Using these b-matrix calculations, SPEN's ability to deliver DTI measurements was tested on phantoms as well as ex vivo and in vivo. In the latter case, DTI involved scans on mice brains and on human lactating breasts. For both ex vivo and in vivo investigations, SPEN data proved less sensitive to distortions arising from Bo field inhomogeneities and from eddy currents, than conventional single-shot alternatives. Further resolution enhancement could be achieved using referenceless methods for interleaved SPEN data acquisitions. The robustness of SPEN-based sequences vis-à-vis field instabilities and heterogeneities, enables the implementation of DTI experiments with good sensitivity and resolution even in challenging environments in both preclinical and clinical settings. Magn Reson Med 77:1124-1133, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270884/pdf
Ending Page	1133
Page Count	10
Starting Page	1124
e-ISSN	15222594
DOI	10.1002/mrm.26197
Journal	Magnetic Resonance in Medicine
Issue Number	3
Volume Number	77
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2016-03-10
Access Restriction	Open
Subject Keyword	Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging B-value Calculations Brain Dti Breast Dti Diffusion-tensor Imaging - Dti Spatiotemporal Encoding - Spen
Content Type	Text
Resource Type	Article

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