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Lung perfusion measured using magnetic resonance imaging: New tools for physiological insights into the pulmonary circulation
| Content Provider | Scilit |
|---|---|
| Author | Md, Susan R. Hopkins Prisk, G. Kim |
| Copyright Year | 2010 |
| Description | Journal: Journal of Magnetic Resonance Imaging (JMRI) Since the lung receives the entire cardiac output, sophisticated imaging techniques are not required in order to measure total organ perfusion. However, for many years studying lung function has required physiologists to consider the lung as a single entity: in imaging terms as a single voxel. Since imaging, and in particular functional imaging, allows the acquisition of spatial information important for studying lung function, these techniques provide considerable promise and are of great interest for pulmonary physiologists. In particular, despite the challenges of low proton density and short T2* in the lung, noncontrast MRI techniques to measure pulmonary perfusion have several advantages including high reliability and the ability to make repeated measurements under a number of physiologic conditions. This brief review focuses on the application of a particular arterial spin labeling (ASL) technique, ASL‐FAIRER (flow sensitive inversion recovery with an extra radiofrequency pulse), to answer physiologic questions related to pulmonary function in health and disease. The associated measurement of regional proton density to correct for gravitational‐based lung deformation (the “Slinky” effect (Slinky is a registered trademark of Pauf‐Slinky incorporated)) and issues related to absolute quantification are also discussed. J. Magn. Reson. Imaging 2010;32:1287–1301. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359842/pdf |
| Ending Page | 1301 |
| Page Count | 15 |
| Starting Page | 1287 |
| e-ISSN | 15222586 |
| DOI | 10.1002/jmri.22378 |
| Journal | Journal of Magnetic Resonance Imaging (JMRI) |
| Issue Number | 6 |
| Volume Number | 32 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-11-23 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Magnetic Resonance Imaging (JMRI) Radiology, Nuclear Medicine and Imaging Pulmonary Perfusion Functional Lung Imaging |
| Content Type | Text |
| Resource Type | Article |
