NDLI: Confidence Bands for Low‐Dose Risk Estimation with Quantal Response Data

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Confidence Bands for Low‐Dose Risk Estimation with Quantal Response Data

Content Provider	Scilit
Author	Al-Saidy, Obaid M. Piegorsch, Walter W. West, R. Webster Nitcheva, Daniela K.
Copyright Year	2003
Description	Journal: Biometrics We study the use of simultaneous confidence bands for low-dose risk estimation with quantal response data, and derive methods for estimating simultaneous upper confidence limits on predicted extra risk under a multistage model. By inverting the upper bands on extra risk, we obtain simultaneous lower bounds on the benchmark dose (BMD). Monte Carlo evaluations explore characteristics of the simultaneous limits under this setting, and a suite of actual data sets are used to compare existing methods for placing lower limits on the BMD.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.0006-341X.2003.00121.x/pdf
Ending Page	1062
Page Count	7
Starting Page	1056
e-ISSN	15410420
DOI	10.1111/j.0006-341x.2003.00121.x
Journal	Biometrics
Issue Number	4
Volume Number	59
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2003-12-11
Access Restriction	Open
Subject Keyword	Journal: Biometrics Mathematical Social Sciences Benchmark Analysis Benchmark Dose Carcinogenic Risk Assessment Low‐dose Extrapolation Multistage Model Quantal Data Quantitative Risk Analysis Simultaneous Confidence Bounds
Content Type	Text
Resource Type	Article

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