NDLI: Rapid Increase of Pneumococcal Resistance to β-Lactam and Other Antibiotics in Isolates from the Respiratory Tract (Nagasaki, Japan: 1975-1994)

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Rapid Increase of Pneumococcal Resistance to β-Lactam and Other Antibiotics in Isolates from the Respiratory Tract (Nagasaki, Japan: 1975-1994)

Content Provider	Scilit
Author	Rikitomi, Naoto Sow, Papa Salif Watanabe, Kiwao Nunez, Duilio S. Martinez, Glenda Nagatake, Tsuyoshi
Copyright Year	1996
Description	Journal: Microbiology and Immunology The susceptibility of 101 pneumococcal isolates from the respiratory tract during 1991-1994 was examined and compared with the susceptibility of isolates over the period of 1975-1990. A rapid increase of resistance was seen not only to penicillin but also other antimicrobial agents. During 1991-1994, 38% of all the isolates were resistant to penicillin. The rates of resistance during this period were 16-23% for three newer cephalosporins, 18% for imipenem, 69% for tetracycline, 31% for erythromycin, 20% for chloramphenicol and 9% for clindamycin. The use of antibiotics within one month prior to pneumococcal isolation was correlated with penicillin resistance (P < 0.05). Serotyping of the isolates by antiserum revealed differences in predominant types between penicillin-resistant (19F, 23F,4) and -susceptible isolates (15, 4, 11A). Our data suggests that anti-pneumococcal antibiotics should be carefully chosen on the basis of susceptibility tests.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1348-0421.1996.tb01158.x/pdf
Ending Page	905
Page Count	7
Starting Page	899
ISSN	03855600
e-ISSN	13480421
DOI	10.1111/j.1348-0421.1996.tb01158.x
Journal	Microbiology and Immunology
Issue Number	12
Volume Number	40
Language	English
Publisher	Wiley-Blackwell
Publisher Date	1996-12-01
Access Restriction	Open
Subject Keyword	Journal: Microbiology and Immunology Metallurgy and Metallurgical Engineering Streptococcus Pneumoniae Penicillin‐resistant Pneumococcus Multiply Resistant Pneumococcus Respiratory Infection
Content Type	Text
Resource Type	Article
Subject	Virology Immunology Microbiology

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Rapid Increase of Pneumococcal Resistance to β-Lactam and Other Antibiotics in Isolates from the Respiratory Tract (Nagasaki, Japan: 1975-1994)

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