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PC HYPR flow: A technique for rapid imaging of contrast dynamics
| Content Provider | Scilit |
|---|---|
| Author | Velikina, Julia V. Johnson, Kevin M. Wu, Yijing Samsonov, Alexey A. Turski, Patrick Mistretta, Charles A. |
| Copyright Year | 2010 |
| Description | Journal: Journal of Magnetic Resonance Imaging (JMRI) Purpose: To improve spatial and temporal resolution and signal‐to‐noise ratio (SNR) in three‐dimensional (3D) radial contrast‐enhanced (CE) time‐resolved MR angiography by means of a novel hybrid phase contrast (PC) and CE MRA acquisition and HYPR reconstruction (PC HYPR Flow). Materials and Methods: PC HYPR Flow consists of a CE exam immediately followed by a PC scan used to constrain the HYPR reconstruction of the time series. Temporal resolution of the new method was studied in computer simulations. The feasibility of the new technique was studied in healthy subjects and patients with brain arteriovenous malformations and in a canine model of aneurysms. Results: Simulations demonstrated preservation of contrast agent dynamics in proximal vessels, showing better performance than peer methods for acceleration up to 20 in 2D. In vivo, PC HYPR Flow yielded 3D time series with frame rate of 0.5 s and significantly outperformed two peer methods by means of a major increase in spatial resolution (0.8 × 0.8 × 0.8 $mm^{3}$) and arterial/venous ratio, while maintaining necessary temporal waveform fidelity and high SNR. Conclusion: This initial study indicates that PC HYPR Flow simultaneously provides 3D isotropic sub‐millimeter spatial resolution, sub‐second temporal reconstruction windows and high SNR level, which may benefit a wide range of CE MRA applications. J. Magn. Reson. Imaging 2010; 31: 447–456. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897749/pdf |
| Ending Page | 456 |
| Page Count | 10 |
| Starting Page | 447 |
| e-ISSN | 15222586 |
| DOI | 10.1002/jmri.22035 |
| Journal | Journal of Magnetic Resonance Imaging (JMRI) |
| Issue Number | 2 |
| Volume Number | 31 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-01-23 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Magnetic Resonance Imaging (JMRI) Radiology, Nuclear Medicine and Imaging Constrained Reconstruction Contrast Enhanced Mra Phase Contrast Mra Radial Trajectory |
| Content Type | Text |
| Resource Type | Article |
