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CONFORMATIONAL ENERGY CALCULATIONS ON ENKEPHALINS AND ENKEPHALIN ANALOGS:
| Content Provider | Scilit |
|---|---|
| Author | Manavalan, Parthasarathy Momany, Frank A. |
| Copyright Year | 2009 |
| Description | Journal: International journal of peptide and protein research Conformational energy calculations were carried out on the peptide enkaphalins (ENK) and selected analogs to find those conformers of low energy. The analogs studied include [D-Ala2]Enk-NH2, [D-Ala2]Enk, [D-Met2, Pro5]Enk-NH2, [D-Ala2, D-Phe5]Enk, [D-Ala2, D-Leu5]Enk, [D-Ala2, (N-Me)Phe4, Met5] Enk-NH2 and [D-Ala2, (N-Me)Met5]Enk-NH2. When the low-energy conformers for all the analogs are compared, different allowed backbone conformations are found which orient the functional side-chains such that three classifications of structures appear. Each classification shows a unique configuration of side-chain positions in space even though different backbone conformations are found within each classification. |
| Related Links | http://onlinelibrary.wiley.com/doi/10.1111/j.1399-3011.1981.tb02980.x/pdf |
| Ending Page | 275 |
| Page Count | 20 |
| Starting Page | 256 |
| ISSN | 03678377 |
| DOI | 10.1111/j.1399-3011.1981.tb02980.x |
| Journal | International journal of peptide and protein research |
| Issue Number | 3 |
| Volume Number | 18 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2009-01-12 |
| Access Restriction | Open |
| Subject Keyword | Journal: International journal of peptide and protein research Conformational Energies Different Configurations Low‐energy Conformers |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry |
