NDLI: Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor

Content Provider	Scilit
Author	Calvaresi, Emilia C. Granchi, Carlotta Tuccinardi, Tiziano Bussolo, Valeria Di Huigens, Robert W. Lee, Hyang Yeon Palchaudhuri, Rahul Macchia, Marco Martinelli, Adriano Minutolo, Filippo Hergenrother, Paul J.
Copyright Year	2013
Description	Journal: ChemBioChem Effective glucose diet: We report the development and activity of glucose-conjugated LDH-A inhibitors designed for dual targeting of the Warburg effect (elevated glucose uptake and glycolysis) in cancer cells. Glycoconjugation could be applied to inhibitors of many enzymes involved in glycolysis or tumor metabolism.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919968/pdf
Ending Page	2267
Page Count	5
Starting Page	2263
e-ISSN	14397633
DOI	10.1002/cbic.201300562
Journal	ChemBioChem
Issue Number	17
Volume Number	14
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2013-10-31
Access Restriction	Open
Subject Keyword	Journal: ChemBioChem Medicinal Chemistry Targeted Anticancer Agents
Content Type	Text
Resource Type	Article

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Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor