NDLI: Advanced Functional Nanomaterials for Theranostics

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Advanced Functional Nanomaterials for Theranostics

Content Provider	Scilit
Author	Huang, Haoyuan Lovell, Jonathan F.
Copyright Year	2016
Description	Journal: Advanced Functional Materials Nanoscale materials have been explored extensively as agents for therapeutic and diagnostic (i.e. theranostic) applications. Research efforts have shifted from exploring new materials in vitro to designing materials that function in more relevant animal disease models, thereby increasing potential for clinical translation. Current interests include non-invasive imaging of diseases, biomarkers and targeted delivery of therapeutic drugs. Here, we discuss some general design considerations of advanced theranostic materials and challenges of their use, from both diagnostic and therapeutic perspectives. Common classes of nanoscale biomaterials, including magnetic nanoparticles, quantum dots, upconversion nanoparticles, mesoporous silica nanoparticles, carbon-based nanoparticles and organic dye-based nanoparticles, have demonstrated potential for both diagnosis and therapy. Variations such as size control and surface modifications can modulate biocompatibility and interactions with target tissues. The needs for improved disease detection and enhanced chemotherapeutic treatments, together with realistic considerations for clinically translatable nanomaterials will be key driving factors for theranostic agent research in the near future.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560626/pdf
ISSN	1616301X
e-ISSN	16163028
DOI	10.1002/adfm.201603524
Journal	Advanced Functional Materials
Issue Number	2
Volume Number	27
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2016-11-07
Access Restriction	Open
Subject Keyword	Journal: Advanced Functional Materials Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Biomaterials Electronic, Optical and Magnetic Materials Condensed Matter Physics Electrochemistry

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