NDLI: Nucleotide Sequence at the 5' Extremity of Tobacco-Mosaic-Virus RNA. 2. The Coding Region (Nucleotides 69-236)

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Nucleotide Sequence at the 5' Extremity of Tobacco-Mosaic-Virus RNA. 2. The Coding Region (Nucleotides 69-236)

Content Provider	Scilit
Author	Jonard, Gérard Richards, Kenneth Mohier, Eliane Gerlinger, Pierre
Copyright Year	1978
Description	Journal: Journal of Biological Inorganic Chemistry In the preceding paper it was shown that the first A-U-G codon in tobacco mosaic virus RNA is separated from the 5' terminus by a sequence of 68 nucleotides devoid of internal guanosine residues. In this paper we present the sequence of 165 residues immediately following the first potential initiation codon. The characterized sequence contains four nonsense codons but none are in phase with the prospective initiation codon. Several lines of evidence, including direct characterization of the portion of the RNA molecule which binds to and is protected by the ribosome in the course of initiation, all support the idea that the A-U-G at position 69-71 is a functional initiation signal for viral protein synthesis.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1978.tb12195.x/pdf
Ending Page	531
Page Count	11
Starting Page	521
ISSN	09498257
e-ISSN	14321327
DOI	10.1111/j.1432-1033.1978.tb12195.x
Journal	Journal of Biological Inorganic Chemistry
Issue Number	2
Volume Number	84
Language	English
Publisher	Wiley-Blackwell
Publisher Date	1978-03-01
Access Restriction	Open
Subject Keyword	Journal: Journal of Biological Inorganic Chemistry Virus Rna Preceding Paper Initiation Codon
Content Type	Text
Resource Type	Article
Subject	Biochemistry Inorganic Chemistry

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