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Retinal Phototoxicity Induced by Hydrochlorothiazide After Exposure to a UV Tanning Device
| Content Provider | Scilit |
|---|---|
| Author | Costagliola, Ciro Menzione, Massimo Chiosi, Flavia Romano, Mario R. Corte, Michele D. E. L. L. A. Rinaldi, Michele |
| Copyright Year | 2008 |
| Description | Journal: Photochemistry and Photobiology UV radiation is known to cause acute and chronic eye and skin damage. The present case report describes the occurrence of hydrochlorothiazide-induced retinal phototoxicity immediately after exposure to UV light emanated from a sunbed in a 40-year-old myopic woman. During the tanning session she had always worn UV protective eyewear, except for a few minutes when she took the protective goggles off to put her spectacles on to locate and turn the timer switch off. At baseline her visual acuity was 10/25 in OD and 10/80 in OS. Fundus examination revealed the presence of retinal lesions in both eyes. More specific tests confirmed the presence of a phototoxic macular damage. Hydrochlorothiazide was discontinued, and she was recommended to wear UV filtering glasses. Over the follow-up period (12 months), a slow and progressive visual acuity recovery in both eyes occurred. At the last check the visual acuity improvement was of about 60% from baseline in both eyes. Fundus examination showed only a juxtafoveal flat pigmented scar of the retinal pigment epithelium in both eyes, milder in OD. The constant rise in the number of sunbed users makes the knowledge of UV-related side effects a problem that cannot be postponed further. Awareness of the general public about the harmful effects of UV exposure must represent one of the leading preventive health strategies. Therefore, a careful analysis of the medical history before the admission to a sunbed session throughout a questionnaire could represent an economic and effective measure to avoid further cases of a phototoxic macular damage in patients taking photosensitizing compounds. |
| Related Links | http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2008.00404.x/pdf |
| Ending Page | 1297 |
| Page Count | 4 |
| Starting Page | 1294 |
| e-ISSN | 17511097 |
| DOI | 10.1111/j.1751-1097.2008.00404.x |
| Journal | Photochemistry and Photobiology |
| Issue Number | 5 |
| Volume Number | 84 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2008-09-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Photochemistry and Photobiology |
| Content Type | Text |
| Resource Type | Article |
