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Treatment of Premenstrual Mastalgia with Tamoxifen
| Content Provider | Scilit |
|---|---|
| Author | Messinis, Ioannis E. Lolis, Dimitrios |
| Copyright Year | 1988 |
| Description | Journal: Acta Obstetricia et Gynecologica Scandinavica Thirty-four women with normal menstrual cycles but suffering from severe premenstrual mastalgia were randomly treated with either tamoxifen (10 mg daily) (18 women) or placebo (16 women) from cycle day 5 to 24 for six consecutive cycles. At the end of the treatment, 89% of the tamoxifen-treated patients were free from the symptoms and the remainder experienced partial alleviation. In contrast, six patients treated with placebo showed only partial alleviation (38%)(p < 0.001). Twelve months after the end of tamoxifen treatment, 53% of the medicated women were still free of symptoms as compared with none of the placebo-treated patients. These results suggest that tamoxifen is highly effective for the management of severe premenstrual mastalgia and should be useful for the treatment of this disorder. |
| Related Links | https://obgyn.onlinelibrary.wiley.com/doi/10.1111/j.1600-0412.1988.tb07804.x |
| Ending Page | 309 |
| Page Count | 3 |
| Starting Page | 307 |
| ISSN | 00016349 |
| e-ISSN | 16000412 |
| DOI | 10.3109/00016348809004225 |
| Journal | Acta Obstetricia et Gynecologica Scandinavica |
| Issue Number | 4 |
| Volume Number | 67 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 1988-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Obstetricia et Gynecologica Scandinavica Obstetrics and Gynecology Partial Alleviation Severe Premenstrual Mastalgia |
| Content Type | Text |
| Resource Type | Article |
| Subject | Obstetrics and Gynecology |
