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Simultaneous $T_{1}$ and $B_{1} ^{+}$ Mapping Using Reference Region Variable Flip Angle Imaging

Content Provider	Scilit
Author	Sung, Kyunghyun Saranathan, Manojkumar Daniel, Bruce L. Hargreaves, Brian A.
Copyright Year	2013
Description	Journal: Magnetic Resonance in Medicine To present a new method that can simultaneously and efficiently measure T1 and B1 (+) maps using reference region variable flip angle (RR-VFA) imaging. Assuming T1 relaxation time in a reference region such as fat is well characterized, and the reference region sufficiently covers smoothly varying B1 (+) field inhomogeneity, B1 (+) maps can be measured from VFA images, conventionally used for T1 measurements. Fat-only images from two-point Dixon acquisitions were used to compute B1 (+) maps, and the B1 (+) maps were compared with ones using the double-angle method (DAM) in 22 breast MRI patients at 3T. Additionally, high spatial resolution VFA images were acquired to show T1 measurements with and without the RR-VFA B1 (+) correction in six patients. RR-VFA is able to generate reliable B1 (+) maps, similar to those using the conventional DAM. This simultaneous T1 and B1 (+) mapping can also be used to reduce T1 estimation errors, where T1 maps have more uniform fibroglandular tissue T1 and better depiction of heterogeneous T1 of breast masses. A new method that can measure both T1 and B1 (+) maps based on Dixon VFA images is described, offering improved T1 quantification with no scan time penalty.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923865/pdf
Ending Page	961
Page Count	8
Starting Page	954
e-ISSN	15222594
DOI	10.1002/mrm.24904
Journal	Magnetic Resonance in Medicine
Issue Number	4
Volume Number	70
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2013-08-13
Access Restriction	Open
Subject Keyword	Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging B1 Field Inhomogeneity T1 Mapping Breast Imaging High‐field Mri Quantitative Dce‐mri
Content Type	Text
Resource Type	Article

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