Loading...
Please wait, while we are loading the content...
Similar Documents
Customized fetal growth standard compared with the INTERGROWTH-21st century standard at predicting small-for-gestational-age neonates
| Content Provider | Scilit |
|---|---|
| Author | Odibo, Anthony O. Nwabuobi, Chinedu Odibo, Linda Leavitt, Karla Obican, Sarah Tuuli, Methodius G. |
| Copyright Year | 2018 |
| Description | Journal: Acta Obstetricia et Gynecologica Scandinavica Introduction The Intergrowth‐21st project (IG‐21) was recently performed aiming to provide a universal benchmark for comparing fetal growth across different ethnicities. Our aim was to compare the IG‐21 with a customized standard for predicting pregnancies at risk for neonatal small for gestational age (SGA) and adverse outcomes. Material and methods This was a prospective cohort study including singleton pregnancies presenting for fetal growth assessment between 26 and 36 weeks gestation. Fetal growth restriction was defined as the estimated fetal weight < 10th percentile for gestational age using IG‐21 and a customized standard. Neonatal SGA was defined as birthweight < 10th percentile for gestational age by the Alexander chart. Primary outcome was the prediction of neonatal SGA. Secondary outcomes included a composite of adverse neonatal outcomes. The discriminatory ability of each growth standard was compared using area under receiver operating characteristic curves (AUC). Results Of 1054 pregnancies meeting the inclusion criteria, the incidence of neonatal SGA was 139 (13.2%), and a composite adverse neonatal outcome occurred in 300 (28.4%). The sensitivity of the customized standard (38.8%) was higher than IG‐21 (24.5%) for predicting neonatal SGA, with AUC (95% CI) of 0.67, (0.63‐0.71) for customized versus 0.62 (0.58‐0.65) for IG‐21; p=0.003. Both standards were comparable in predicting the composite adverse neonatal outcomes: AUC (95% CI) 0.52 (0.50‐0.55) for customized versus and 0.51 (0.50‐0.53) for IG‐21; p=0.25. Conclusion Both growth standards had modest performance in detecting neonatal SGA and were poor at predicting short term adverse neonatal outcome. This article is protected by copyright. All rights reserved. |
| Ending Page | 1387 |
| Starting Page | 1381 |
| ISSN | 00221295 |
| e-ISSN | 16000412 |
| DOI | 10.1111/aogs.13394 |
| Journal | Acta Obstetricia et Gynecologica Scandinavica |
| Issue Number | 11 |
| Volume Number | 97 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2018-06-07 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Obstetricia et Gynecologica Scandinavica Obstetrics and Gynecology Small‐for‐gestational Age Fetal Growth Standard Adverse Neonatal Outcome |
| Content Type | Text |
| Resource Type | Article |
| Subject | Obstetrics and Gynecology |
