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Effect of a novel essential oil mouthrinse without alcohol on gingivitis: a double-blinded randomized controlled trial
| Content Provider | Scilit |
|---|---|
| Author | Botelho, Marco Antonio Filho, José Gomes Bezerra Correa, Luciano Lima Fonseca, Said Gonçalves da Cruz Gapski, Ricardo Brito, Gerly Anne Castro Heukelbach, Jörg |
| Copyright Year | 2007 |
| Description | Several different plant extracts have been evaluated with respect to their antimicrobial effects against oral pathogens and for reduction of gingivitis. Given that a large number of these substances have been associated with significant side effects that contraindicate their long-term use, new compounds need to be tested. The aim of this study was to assess the short-term safety and efficacy of a Lippia sidoides ("alecrim pimenta")-based essential oil mouthrinse on gingival inflammation and bacterial plaque. Fifty-five patients were enrolled into a pilot, double-blinded, randomized, parallel-armed study. Patients were randomly assigned to undergo a 7-day treatment regimen with either the L. sidoides-based mouthrinse or 0.12% chlorhexidine mouthrinse. The results demonstrated decreased plaque index, gingival index and gingival bleeding index scores at 7 days, as compared to baseline. There was no statistically significance difference (p>0.05) between test and control groups for any of the clinical parameters assessed throughout the study. Adverse events were mild and transient. The findings of this study demonstrated that the L. sidoides-based mouthrinse was safe and efficacious in reducing bacterial plaque and gingival inflammation. |
| Related Links | http://www.scielo.br/pdf/jaos/v15n3/a05v15n3.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327463/pdf http://www.scielo.br/scielo.php?script=sci_pdf&pid=S1678-77572007000300005&lng=en&nrm=iso&tlng=en |
| Ending Page | 180 |
| Page Count | 6 |
| Starting Page | 175 |
| ISSN | 16787757 |
| e-ISSN | 16787765 |
| DOI | 10.1590/s1678-77572007000300005 |
| Journal | Journal of Applied Oral Science |
| Issue Number | 3 |
| Volume Number | 15 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 2007-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal of Applied Oral Science Dentistry and Oral Surgery Integrative and Complementary Medicine Lippia Sidoides Essential Oil Randomized Controlled Clinical Trial |
| Content Type | Text |
| Resource Type | Article |
| Subject | Dentistry Medicine |
