NDLI: Lipoprotein (a) and cardiovascular risk factors in children and adolescents

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Lipoprotein (a) and cardiovascular risk factors in children and adolescents

Content Provider	Scilit
Author	Jos, é De Alencar F. Palmeira, Astrid Camelo Leal, Adriana Amorim De F. Ramos, Nathaly De Medeiros N. Neto, José De Alencar Fernandes Simões, Mônica Oliveira Da S. Medeiros, Carla Campos M.
Copyright Year	2013
Description	OBJECTIVE: To review the relationship between lipoprotein (a) [Lp(a)] and other risk factors for cardiovascular disease (CVD) in children and adolescents. DATA SOURCES: This systematic review included studies from 2001 to 2011, a ten-year time period. Epidemiological studies with children and/or adolescents published in English, Portuguese or Spanish and fully available online were included. The searches were performed in Science Direct, PubMed/Medline, BVS (Biblioteca Virtual em Saúde) and Cochrane Library databases, using the following combination of key-words: "lipoprotein a" and "cardiovascular diseases" and "obesity". DATA SYNTHESIS: Overall, 672 studies were obtained but only seven were included. Some studies assessed the family history for CVD. In all of them, Lp(a) levels were increased in patients with family history for CVD. There was also a positive correlation between Lp(a) and LDL-cholesterol, total cholesterol, and apolipoprotein B levels, suggesting an association between Lp(a) levels and the lipid profile. CONCLUSIONS: The evidence that CVD may originate in childhood and adolescence leads to the need for investigating the risk factors during this period in order to propose earlier and possibly more effective interventions to reduce morbidity and mortality rates.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183047/pdf http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0103-05822013000400531&lng=en&nrm=iso&tlng=en
Ending Page	537
Page Count	7
Starting Page	531
ISSN	01030582
e-ISSN	19840462
DOI	10.1590/s0103-05822013000400017
Journal	Revista Paulista de Pediatria
Issue Number	4
Volume Number	31
Language	English
Publisher	FapUNIFESP (SciELO)
Publisher Date	2013-12-01
Access Restriction	Open
Subject Keyword	Revista Paulista de Pediatria Pediatrics and Child Health Cardiovascular Diseases Enfermedades Cardiovasculares Doenças Cardiovasculares
Content Type	Text
Resource Type	Article
Subject	Pediatrics, Perinatology and Child Health

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