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Seleção de plantas com atividade anticolinasterase para tratamento da doença de Alzheimer
| Content Provider | Scilit |
|---|---|
| Author | Trevisan, Maria Teresa Salles Macedo, Fábio Vanderlan Viana van de Meent, Michiel Verpoorte, Rob |
| Copyright Year | 2003 |
| Description | Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognite impairment and personality changes. The development of drugs for the treatment of the cognitive deficits of AD has focused on agents which counteract loss in cholinergic activities. These symptons of AD have been successfully treated with acetylcholinesterase (AchE) inhibitors (eg. galanthamine). There still is great interest in finding better AchE inhibitors. We use Ellmann's microplate assay and silica gel thin-layer chromatography (TLC) to screen natural products from plants as new sources of AchE inhibitors |
| Related Links | http://www.scielo.br/pdf/qn/v26n3/15651.pdf http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0100-40422003000300002&lng=pt&nrm=iso&tlng=pt |
| Ending Page | 304 |
| Page Count | 4 |
| Starting Page | 301 |
| ISSN | 01004042 |
| e-ISSN | 01004042 |
| DOI | 10.1590/s0100-40422003000300002 |
| Journal | Química Nova |
| Issue Number | 3 |
| Volume Number | 26 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 2003-05-01 |
| Access Restriction | Open |
| Subject Keyword | Química Nova Plantas Com Tratamento Da Da Doena Para Tratamento Atividade Anticolinasterase Anticolinasterase Para |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry |