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Experimental model of ultrasound thermotherapy in rats inoculated with Walker-236 tumor
| Content Provider | Scilit |
|---|---|
| Author | Morano, José Antonio Carlos Otaviano David Cordeiro, Naylana Guimarães, Sergio Botelho Jamacaru, Francisco Vagnaldo Fechine Filho, Manoel Odorico De Moraes |
| Copyright Year | 2011 |
| Description | PURPOSE: To develop a model to evaluate the effects of focal pulsed ultrasound (US) waves as a source of heat for treatment of murine subcutaneous implanted Walker tumor. METHODS: An experimental, controlled, comparative study was conducted. Twenty male Wistar rats (160-300 g) randomized in 2 equal groups (G-1: Control and G-2: Hyperthermia) were inoculated with Walker-256 carcinosarcoma tumor. After 5 days G-2 rats were submitted to 45ºC hyperthermia. Heat was delivered directly to the tumor by an ultrasound (US) equipment (3 MHz frequency, 1,5W/cm³). Tumor temperature reached 45º C in 3 minutes and was maintained at this level for 5 minutes. Tumor volume was measured on days 5, 8, 11, 14 e 17 post inoculation in both groups. Unpaired t-test was used for comparison. P |
| Related Links | http://www.scielo.br/pdf/acb/v26s1/11.pdf |
| Ending Page | 56 |
| Page Count | 4 |
| Starting Page | 53 |
| ISSN | 01028650 |
| e-ISSN | 16782674 |
| DOI | 10.1590/s0102-86502011000700011 |
| Journal | Acta Cirurgica Brasileira |
| Issue Number | suppl 1 |
| Volume Number | 26 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 2011-01-01 |
| Access Restriction | Open |
| Subject Keyword | Acta Cirurgica Brasileira Acoustics and Ultrasonics Pediatrics and Child Health Animal Experimentation Carcinoma 256 De Walker Experimentação Animal Hipertermia Induzida |
| Content Type | Text |
| Resource Type | Article |
| Subject | Surgery |
