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Multifactorial control of water and saline intake: role of a2-adrenoceptors
| Content Provider | Scilit |
|---|---|
| Author | De-Luca Jr., L. A. Menani, J. V. |
| Copyright Year | 1997 |
| Description | Water and saline intake is controlled by several mechanisms activated during dehydration. Some mechanisms, such as the production of angiotensin II and unloading of cardiovascular receptors, activate both behaviors, while others, such as the increase in blood osmolality or sodium concentration, activate water, but inhibit saline intake. Aldosterone probably activates only saline intake. Clonidine, anα2-adrenergic agonist, inhibits water and saline intake induced by these mechanisms. One model to describe the interactions between these multiple mechanisms is a wire-block diagram, where the brain circuit that controls each intake is represented by a summing point of its respective inhibiting and activating factors. The α2-adrenoceptors constitute an inhibitory factor common to both summing points |
| Related Links | http://www.scielo.br/pdf/bjmbr/v30n4/2789C.pdf http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0100-879X1997000400011&lng=en&nrm=iso&tlng=en |
| Ending Page | 502 |
| Page Count | 6 |
| Starting Page | 497 |
| ISSN | 0100879X |
| e-ISSN | 1414431X |
| DOI | 10.1590/s0100-879x1997000400011 |
| Journal | Brazilian Journal of Medical and Biological Research |
| Issue Number | 4 |
| Volume Number | 30 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 1997-04-01 |
| Access Restriction | Open |
| Subject Keyword | Brazilian Journal of Medical and Biological Research Renin Angiotensin System Sodium Chloride Renin Angiotensin Aldosterone System Alpha 2 Adrenergic Receptor |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neuroscience Cell Biology Physiology Medicine Biochemistry Biophysics Immunology Pharmacology, Toxicology and Pharmaceutics |