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Titration of serum anti-ganglioside antibodies in patients with chronic medular injury previous to treatment with GM1 ganglioside
| Content Provider | Scilit |
|---|---|
| Author | Filho, Tarcísio Eloy Pessoa Barros Filho, Ciro da Silva |
| Copyright Year | 2003 |
| Description | Anti-ganglioside serum titers were evaluated by ELISA in 150 patients with complete spinal cord lesion for 6 to 12 months (IgG monosialo GM1, IgM monosialo GM1, IgG asialo GM1, IgM asialo GM1, IgG disialo GD1b e IgM disialo GD1b) prior to treatment with GM1 100 mg/day i.m. Only 4 patients showed positive titers for anti-asialo-GM1 (IgM) antibodies . All patients were clinically examined during and after treatment. No important side effects were observed with GM1 therapy. These results suggest that GM1-ganglioside administration in patients with chronic spinal cord injury is safe. |
| Related Links | http://www.scielo.br/pdf/aob/v11n2/a01v11n2.pdf |
| Ending Page | 71 |
| Page Count | 3 |
| Starting Page | 69 |
| ISSN | 14137852 |
| e-ISSN | 18094406 |
| DOI | 10.1590/s1413-78522003000200001 |
| Journal | Acta Ortopedica Brasileira |
| Issue Number | 2 |
| Volume Number | 11 |
| Language | English |
| Publisher | FapUNIFESP (SciELO) |
| Publisher Date | 2003-04-01 |
| Access Restriction | Open |
| Subject Keyword | Acta Ortopedica Brasileira Medical Laboratory Technology Spinal Cord Injuries Traumatismos Da Medula Espinhal |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Rehabilitation Physical Therapy, Sports Therapy and Rehabilitation |
