NDLI: Estimating the cost-effectiveness of pneumococcal conjugate vaccination in Brazil

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Estimating the cost-effectiveness of pneumococcal conjugate vaccination in Brazil

Content Provider	Scilit
Author	Vespa, Glaucia Constenla, Dagna O. Pepe, Camila Safadi, Marco Berezin, Eitan Moraes, José Cássio De Campos, Carlos Alberto Herrerias De Araujo, Denizar Vianna Andrade, Ana Lucia S. S. De
Copyright Year	2009
Description	OBJECTIVE: To compare the costs and benefits of pneumococcal conjugate vaccination compared with no vaccination from the perspectives of the health care system and society. METHODS: Using data from established sources, we estimated the incidence and mortality due to invasive pneumococcal disease, pneumonia, and acute otitis media (AOM) for a hypothetical birth cohort of children from birth to 5 years. RESULTS: A universal pneumococcal conjugate vaccination program was estimated capable of annually avoiding 1 047 cases of invasive disease, 58 226 cases of pneumonia, and 209 862 cases of AOM. When herd immunity effects were considered, the program prevented 1.3 million cases of pneumococcal disease and over 7 000 pneumococcal deaths. At a vaccination cost of R$ 51.12 (US$ 26.35) per dose, vaccination would cost annually R$ 4 289 (US$ 2,211) per disability-adjusted life years averted. This does not take into account herd immunity effects. CONCLUSIONS: At the current vaccine price, conjugate vaccination could be a cost-effective investment compared to other options to control childhood diseases. Further analysis is required to determine whether vaccination at the current price is affordable to Brazil.
Related Links	https://scielosp.org/article/ssm/content/raw/?resource_ssm_path=/media/assets/rpsp/v26n6/07.pdf
Ending Page	528
Page Count	11
Starting Page	518
ISSN	10204989
e-ISSN	16805348
DOI	10.1590/s1020-49892009001200007
Journal	Revista Panamericana de Salud Pública
Issue Number	6
Volume Number	26
Language	English
Publisher	FapUNIFESP (SciELO)
Publisher Date	2009-12-01
Access Restriction	Open
Subject Keyword	Revista Panamericana de Salud Pública Pediatrics and Child Health Pneumococcal Conjugate Conjugate Vaccination Vaccination Cost
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health

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