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Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses

Content Provider	Scilit
Author	Pilau, Marciele Ribas Alves, Sydney Hartz Weiblen, Rudi Arenhart, Sandra Cueto, Ana Paula Lovato, Luciane Teresinha
Copyright Year	2011
Description	Mexican oregano (Lippia graveolens) is a plant found in Mexico and Central America that is traditionally used as a medicinal herb. In the present study, we investigated the antiviral activity of the essential oil of Mexican oregano and its major component, carvacrol, against different human and animal viruses. The MTT test (3-4,5-dimethythiazol-2yl)-2,5-diphenyl tetrazolium bromide) was conducted to determine the selectivity index (SI) of the essential oil, which was equal to 13.1, 7.4, 10.8, 9.7, and 7.2 for acyclovir-resistant herpes simplex virus type 1 (ACVR-HHV-1), acyclovir-sensitive HHV-1, human respiratory syncytial virus (HRSV), bovine herpesvirus type 2 (BoHV-2), and bovine viral diarrhoea virus (BVDV), respectively. The human rotavirus (RV) and BoHV-1 and 5 were not inhibited by the essential oil. Carvacrol alone exhibited high antiviral activity against RV with a SI of 33, but it was less efficient than the oil for the other viruses. Thus, Mexican oregano oil and its main component, carvacrol, are able to inhibit different human and animal viruses in vitro. Specifically, the antiviral effects of Mexican oregano oil on ACVR-HHV-1 and HRSV and of carvacrol on RV justify more detailed studies.
Related Links	http://www.scielo.br/pdf/bjm/v42n4/v42n4a49.pdf
Ending Page	1624
Page Count	9
Starting Page	1616
ISSN	15178382
e-ISSN	16784405
DOI	10.1590/s1517-83822011000400049
Journal	Brazilian Journal of Microbiology
Issue Number	4
Volume Number	42
Language	English
Publisher	FapUNIFESP (SciELO)
Publisher Date	2011-12-01
Access Restriction	Open
Subject Keyword	Brazilian Journal of Microbiology Integrative and Complementary Medicine Antimicrobial Activity Rna Virus Dna Virus Condimental Herbs
Content Type	Text
Resource Type	Article
Subject	Microbiology

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Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses.

Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses

ANTIVIRAL ACTIVITY OF THE LIPPIA GRAVEOLENS (MEXICAN OREGANO) ESSENTIAL OIL AND ITS MAIN COMPOUND CARVACROL AGAINST HUMAN AND ANIMAL VIRUSES

Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses

Identification and Quantification of Phenolic Compounds from Mexican Oregano (Lippia graveolens HBK) Hydroethanolic Extracts and Evaluation of Its Antioxidant Capacity

Antimicrobial and antioxidant activities of Mexican oregano essential oils (Lippia graveolens H. B. K.) with different composition when microencapsulated inβ-cyclodextrin

Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens

Mexican oregano (Lippia graveolens) essential oil-in-water emulsions: impact of emulsifier type on the antifungal activity of Candida albicans.

Effectiveness of Mexican oregano essential oil from the Dominican Republic (Lippia graveolens) against maize pests (Sitophilus zeamais and Fusarium verticillioides)

Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses

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Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses.

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