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MB-SWIFT functional MRI during deep brain stimulation in rats
| Content Provider | Scilit |
|---|---|
| Author | Lehto, Lauri J. Idiyatullin, Djaudat Zhang, Jinjin Utecht, Lynn Adriany, Gregor Garwood, Michael Gröhn, Olli Michaeli, Shalom Mangia, Silvia |
| Copyright Year | 2017 |
| Description | Journal: NeuroImage Recently introduced 3D radial MRI pulse sequence entitled Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) having virtually zero acquisition delay was used to obtain functional MRI (fMRI) contrast in rat's brain at 9.4 T during deep brain stimulation (DBS). The results demonstrate that MB-SWIFT allows functional images free of susceptibility artifacts, and provides an excellent fMRI activation contrast in the brain. Flip angle dependence of the MB-SWIFT fMRI signal and elimination of the fMRI contrast while using saturation bands, indicate a blood flow origin of the observed fMRI contrast. MB-SWIFT fMRI modality permits activation studies in the close proximity to an implanted lead, which is not possible to achieve with conventionally used gradient echo and spin echo - echo planar imaging fMRI techniques. We conclude that MB-SWIFT fMRI is a powerful imaging modality for investigations of functional responses during DBS. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671345/pdf |
| Ending Page | 448 |
| Page Count | 6 |
| Starting Page | 443 |
| ISSN | 10538119 |
| DOI | 10.1016/j.neuroimage.2017.08.012 |
| Journal | NeuroImage |
| Volume Number | 159 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2017-10-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: NeuroImage Deep Brain Stimulation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Cognitive Neuroscience |
