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Performance assessment of a new optimization system for robotic SBRT MLC-based plans
| Content Provider | Scilit |
|---|---|
| Author | Calusi, Silvia Doro, Raffaela Cataldo, Vanessa Di Cipressi, Samantha Francolini, Giulio Bonucci, Ivano Livi, Lorenzo Masi, Laura |
| Copyright Year | 2020 |
| Description | Journal: Physica Medica To assess the performance of a new optimization system, VOLO, for CyberKnife MLC-based SBRT plans in comparison with the existing Sequential optimizer. MLC-plans were created for 25 SBRT cases (liver, prostate, pancreas and spine) using both VOLO and Sequential. Monitor units (MU), delivery time (DT), PTV coverage, conformity (nCI), dose gradient (R50%) and OAR doses were used for comparison and combined to obtain a mathematical score (MS) of plan quality for each solution. MS strength was validated by changing parameter weights and by a blinded clinical plan evaluation. The optimization times (OT) and the average segment areas (SA) were also compared. VOLO solutions offered significantly lower mean DT (-19%) and MU (-13%). OT were below 15 min for VOLO, whereas for Sequential, values spanned from 8 to 160 min. SAs were significantly larger for VOLO: on average 10 cm2 versus 7 cm2. VOLO optimized plans achieved a higher MS than Sequential for all tested parameter combinations. PTV coverage and OAR sparing were comparable for both groups of solutions. Although slight differences in R50% and nCI were found, the parameters most affecting MS were MU and DT. VOLO solutions were selected in 80% of cases by both physicians with 88% inter-observer agreement. The good performance of the VOLO optimization system, together with the large reduction in OT, make it a useful tool to improve the efficiency of CK SBRT planning and delivery. The proposed methodology for comparing different planning solutions can be applied in other contexts. |
| Related Links | http://www.physicamedica.com/article/S1120179720300405/pdf |
| Ending Page | 38 |
| Page Count | 8 |
| Starting Page | 31 |
| ISSN | 11201797 |
| DOI | 10.1016/j.ejmp.2020.02.009 |
| Journal | Physica Medica |
| Volume Number | 71 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2020-03-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Physica Medica Mathematical Score Optimization Algorithms Plan Quality Robotic Sbrt Treatment Planning Technique Comparison |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Physics and Astronomy Biophysics |
