NDLI: Genome sequence variation among isolates of monkey B virus ( Macacine alphaherpesvirus 1) from captive macaques

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Genome sequence variation among isolates of monkey B virus ( Macacine alphaherpesvirus 1) from captive macaques

Content Provider	Scilit
Author	Eberle, R. Maxwell, L. K. Nicholson, S. Black, D. Jones-Engel, L.
Copyright Year	2017
Description	Journal: Virology Complete genome sequences of 19 strains of monkey B virus (Macacine alphaherpesvirus 1; BV) isolated from several macaque species were determined. A low level of sequence variation was present among BV isolates from rhesus macaques. Most variation among BV strains isolated from rhesus macaques was located in regions of repetitive or quasi-repetitive sequence. Variation in coding sequences (polypeptides and miRNAs) was minor compared to regions of non-coding sequences. Non-coding sequences in the long and short repeat regions of the genome did however exhibit islands of conserved sequence. Oral and genital isolates from a single monkey were identical in sequence and varied only in the number of iterations of repeat units in several areas of repeats. Sequence variation between BV isolates from different macaque species (different BV genotypes) was much greater and was spread across the entire genome, confirming the existence of different genotypes of BV in different macaque species.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535784/pdf
Ending Page	35
Page Count	10
Starting Page	26
ISSN	00426822
e-ISSN	10960341
DOI	10.1016/j.virol.2017.05.001
Journal	Virology
Volume Number	508
Language	English
Publisher	Elsevier BV
Publisher Date	2017-05-07
Access Restriction	Open
Subject Keyword	Journal: Virology Macacine Alphaherpesvirus 1 Monkey B Virus Genome Sequence
Content Type	Text
Resource Type	Article
Subject	Virology

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