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Stroke symptoms and risk for incident coronary heart disease in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study
| Content Provider | Scilit |
|---|---|
| Author | Colantonio, Lisandro D. Gamboa, Christopher M. Kleindorfer, Dawn O. Carson, April P. Howard, Virginia J. Muntner, Paul Cushman, Mary Howard, George Safford, Monika M. |
| Copyright Year | 2016 |
| Description | Journal: International Journal of Cardiology Background Many adults without cerebrovascular disease report a history of stroke symptoms, which is associated with higher risk for stroke. Because stroke and coronary heart disease (CHD) share many risk factors, we examined the association between a history of stroke symptoms and incident CHD. Methods We analyzed data from 8999 black and 12,499 white REasons for Geographic And Racial Differences in Stroke (REGARDS) study participants without a prior myocardial infarction, stroke or transitory ischemic attack enrolled in 2003–2007 (total participants=21,498, all ≥45years of age). A history of stroke symptoms (i.e., unilateral weakness, unilateral numbness, full-field vision loss, half-field vision loss, understanding problems and communication problems) was assessed at baseline using the Questionnaire for Verifying Stroke-Free Status. Participants were followed for incident CHD and CHD death through December 2011. Results Overall, 3432 (16.0%) participants reported a history of stroke symptoms (1771 [19.7%] blacks and 1661 [13.3%] whites). There were 701 incident CHD events including 209 CHD deaths over a median follow-up of 5.8years. After adjustment for CHD risk factors, hazard ratios (95% confidence interval [95% CI]) for incident CHD associated with reporting any versus no stroke symptoms were 1.26 (1.04–1.51) in the overall population, 1.28 (0.99–1.65) among blacks and 1.23 (0.94–1.61) among whites. Multivariable-adjusted hazard ratios (95% CI) for CHD death associated with any versus no stroke symptoms were 1.50 (1.10–2.06) overall, 1.58 (1.07–2.32) among blacks and 1.41 (0.82–2.43) among whites. Conclusion A history of stroke symptoms is associated with a higher incidence of CHD among black and white adults. |
| Related Links | http://europepmc.org/articles/pmc4983497?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983497/pdf http://www.internationaljournalofcardiology.com/article/S0167527316310373/pdf |
| Ending Page | 128 |
| Page Count | 7 |
| Starting Page | 122 |
| ISSN | 01675273 |
| e-ISSN | 18741754 |
| DOI | 10.1016/j.ijcard.2016.06.030 |
| Journal | International Journal of Cardiology |
| Volume Number | 220 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2016-06-13 |
| Access Restriction | Open |
| Subject Keyword | Journal: International Journal of Cardiology Public, Environmental and Occupational Health Cerebrovascular Disorders |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cardiology and Cardiovascular Medicine |
