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Lack of utility of cigarettes per day cutoffs for clinical and laboratory smoking research
| Content Provider | Scilit |
|---|---|
| Author | Oliver, Jason A. Pacek, Lauren R. Locey, Erin N. Fish, Laura M. Hendricks, Peter S. Pollak, Kathryn I. |
| Copyright Year | 2019 |
| Description | Journal: Addictive behaviors Background: Most clinical and laboratory smoking research studies require that participants smoke at a certain level to be eligible for enrollment. However, there is limited evidence that use of these cutoffs differentiates groups of smokers along clinically meaningful criteria. Methods: Using receiver operating characteristic curves, we analyzed data from daily smokers in the National Epidemiologic Study of Alcohol Use and Related Conditions - III (NESARC-III) to examine the utility of smoking rates for determining whether participants met DSM-5 criteria for tobacco use disorder, experienced nicotine withdrawal or had a history of failed quit attempts. We also examined whether relationships between these variables differed as a function of key sample characteristics. Results: Smoking rate exhibited a weak relationship with the presence of tobacco use disorder (AUC = 0.664), whether individuals experience nicotine withdrawal (AUC = 0.672) and whether individuals had a history of failed quit attempts (AUC = 0.578). The relationship between smoking rate and a history of failed quit attempts was weaker for women than men (p < .05). Otherwise, utility did not differ as a function of sex, race/ethnicity, education, income, or use of multiple tobacco products. Optimal cutoffs varied somewhat across indices, but the largest number of correct classifications occurred at very low smoking rates. Conclusions: Researchers should consider abandoning the use of smoking rate cutoffs to determine study eligibility. If smoking rate cutoffs are used, a rationale should be presented along with justification for the specific cutoff chosen. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708747/pdf |
| Ending Page | 106066 |
| Page Count | 1 |
| Starting Page | 106066 |
| ISSN | 03064603 |
| e-ISSN | 18736327 |
| DOI | 10.1016/j.addbeh.2019.106066 |
| Journal | Addictive behaviors |
| Volume Number | 98 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2019-07-30 |
| Access Restriction | Open |
| Subject Keyword | Journal: Addictive behaviors Substance Abuse Nicotine Dependence |
| Content Type | Text |
| Resource Type | Article |
| Subject | Toxicology Clinical Psychology Psychiatry and Mental Health |
