NDLI: Identification of a novel torque teno mini virus in cerebrospinal fluid from a child with encephalitis

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Identification of a novel torque teno mini virus in cerebrospinal fluid from a child with encephalitis

Content Provider	Scilit
Author	Kang, Yan-Jun Zhou, Mei-Fang Huang, Wei Deng, Chao Yan, Gen Lu, Zhong-Hua
Copyright Year	2017
Description	Journal: Virologica Sinica Anelloviruses are single-strand circular DNA viruses and ubiquitous within the human population. Although there is no direct evidence, many studies have suggested the anelloviruses may be associated with a variety of diseases. In this study, a novel torque teno mini virus (TTMV) was detected in a child with unexplained encephalitis. The detected virus had a circular genome of 2943 nt in length and 3 open reading frames. It shared 45.4% – 35.9% nucleotide identities with known TTMV species and < 35% with the other species of anellovirus, which suggested it might belong to a new species within the genus Betatorquevirus. Phylogenetic analysis based on the amino acid sequences of ORF1 showed that this virus represented a distinct branch within the diversity of anellovirus. Whether this novel anellovirus strain is associated with encephalitis requires further study.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598920/pdf https://link.springer.com/content/pdf/10.1007/s12250-017-4042-3.pdf
Ending Page	544
Page Count	4
Starting Page	541
ISSN	16740769
e-ISSN	1995820X
DOI	10.1007/s12250-017-4042-3
Journal	Virologica Sinica
Issue Number	6
Volume Number	32
Language	English
Publisher	Elsevier BV
Publisher Date	2017-10-17
Access Restriction	Open
Subject Keyword	Journal: Virologica Sinica
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Virology Immunology Molecular Medicine

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