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Mapping the human brain's cortical-subcortical functional network organization
| Content Provider | Scilit |
|---|---|
| Author | Ji, Jie Lisa Spronk, Marjolein Kulkarni, Kaustubh Repovš, Grega Anticevic, Alan Cole, Michael W. |
| Copyright Year | 2018 |
| Description | Journal: Neuroimage Understanding complex systems such as the human brain requires characterization of the system's architecture across multiple levels of organization – from neurons, to local circuits, to brain regions, and ultimately large-scale brain networks. Here we focus on characterizing the human brain's large-scale network organization, as it provides an overall framework for the organization of all other levels. We developed a highly principled approach to identify cortical network communities at the level of functional systems, calibrating our community detection algorithm using extremely well-established sensory and motor systems as guides. Building on previous network partitions, we replicated and expanded upon well-known and recently-identified networks, including several higher-order cognitive networks such as a left-lateralized language network. We expanded these cortical networks to subcortex, revealing 358 highly-organized subcortical parcels that take part in forming whole-brain functional networks. Notably, the identified subcortical parcels are similar in number to a recent estimate of the number of cortical parcels (360). This whole-brain network atlas – released as an open resource for the neuroscience community – places all brain structures across both cortex and subcortex into a single large-scale functional framework, with the potential to facilitate a variety of studies investigating large-scale functional networks in health and disease. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289683/pdf |
| Ending Page | 57 |
| Page Count | 23 |
| Starting Page | 35 |
| ISSN | 10538119 |
| DOI | 10.1016/j.neuroimage.2018.10.006 |
| Journal | Neuroimage |
| Volume Number | 185 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2018-10-03 |
| Access Restriction | Open |
| Subject Keyword | Journal: Neuroimage Brain Connectivity Resting-state Functional Connectivity |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Cognitive Neuroscience |
