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Endovascular Drug Delivery and Drug Elution Systems: First Principles.
| Content Provider | Scilit |
|---|---|
| Author | Tzafriri, Abraham Rami Edelman, Elazer Reuven |
| Copyright Year | 2016 |
| Description | Journal: Interventional Cardiology Clinics Endovascular drug delivery continues to revolutionize the treatment of atherosclerosis in coronary and peripheral vasculature. The key has been to identify biologic agents that can counter the hyperplastic tissue responses to device expansion/implantation and to develop effective local delivery strategies that can maintain efficacious drug levels across the artery wall over the course of device effects. This article reviews the evolution of endovascular drug delivery technology, explains the mechanisms they use for drug release, and provides a quantitative mechanistic framework for relating drug release mode to arterial drug distribution and effect. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661070/pdf http://www.interventional.theclinics.com/article/S2211745816300232/pdf |
| Ending Page | 320 |
| Page Count | 14 |
| Starting Page | 307 |
| ISSN | 22117458 |
| e-ISSN | 22117466 |
| DOI | 10.1016/j.iccl.2016.02.007 |
| Journal | Interventional Cardiology Clinics |
| Issue Number | 3 |
| Volume Number | 5 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2016-07-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Interventional Cardiology Clinics Biomedical Engineering Peripheral Vascular Disease Controlled Release Drug-eluting Stents Drug-filled Stents Polymer-free Stents |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cardiology and Cardiovascular Medicine |
