NDLI: Zebrafish models for attention deficit hyperactivity disorder (ADHD)

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Zebrafish models for attention deficit hyperactivity disorder (ADHD)

Content Provider	Scilit
Author	Fontana, Barbara D. Franscescon, Francini Rosemberg, Denis B. Norton, William H. J. Kalueff, Allan V. Parker, Matthew O.
Copyright Year	2019
Description	Journal: Neuroscience & Biobehavioral Reviews Attention deficit hyperactivity disorder (ADHD) is a common, debilitating neurodevelopmental disorder associated with inattentiveness, pathological hyperactivity and impulsivity. Despite the mounting human and animal evidence, the neurological pathways underlying ADHD remain poorly understood. Novel translational model organisms, such as the zebrafish (Danio rerio), are becoming important tools to investigate genetic and pathophysiological mechanisms of various neuropsychiatric disorders. Here, we discuss ADHD etiology, existing rodent models and their limitations, and emphasize the advantages of using zebrafish to model ADHD. Overall, the growing utility of zebrafish models may improve our understanding of ADHD and facilitate drug discovery to prevent or treat this disorder.
Related Links	https://researchportal.port.ac.uk/portal/files/13161307/Zebrafish_models_for_attention_deficit_hyperactivity_disorder.pdf
ISSN	01497634
e-ISSN	18737528
DOI	10.1016/j.neubiorev.2019.02.009
Journal	Neuroscience & Biobehavioral Reviews
Volume Number	100
Language	English
Publisher	Elsevier BV
Publisher Date	2019-02-16
Access Restriction	Open
Subject Keyword	Journal: Neuroscience & Biobehavioral Reviews Behavioral Sciences
Content Type	Text
Resource Type	Article
Subject	Cognitive Neuroscience Behavioral Neuroscience Neuropsychology and Physiological Psychology

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