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Fatty acid transporting proteins: Roles in brain development, aging, and stroke
| Content Provider | Scilit |
|---|---|
| Author | Zhang, Wenting Chen, Ruiying Yang, Tuo Xu, Na Chen, Jun Gao, Yanqin Stetler, R. Anne |
| Copyright Year | 2017 |
| Description | Journal: Prostaglandins, Leukotrienes & Essential Fatty Acids (plefa) Polyunsaturated fatty acids are required for the brain development and significantly impact aging and stroke. Due to the hydrophobicity of fatty acids, fatty acids transportation related proteins that include fatty acid binding proteins (FABPs), long chain acyl-coA synthase (ACS), fatty acid transportation proteins (FATPs), fatty acid translocase (FAT/CD36) and newly reported major facilitator superfamily domain-containing protein (Mfsd2a) play critical roles in the uptake of various fatty acids, especially polyunsaturated fatty acids. They are not only involved in neurodevelopment, but also have great impact on neurological disease, such as aging related dementia and stroke. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650946/pdf http://www.plefa.com/article/S0952327817300212/pdf |
| Ending Page | 45 |
| Page Count | 11 |
| Starting Page | 35 |
| ISSN | 09523278 |
| e-ISSN | 15322823 |
| DOI | 10.1016/j.plefa.2017.04.004 |
| Journal | Prostaglandins, Leukotrienes & Essential Fatty Acids (plefa) |
| Volume Number | 136 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2017-04-21 |
| Access Restriction | Open |
| Subject Keyword | Journal: Prostaglandins, Leukotrienes & Essential Fatty Acids (plefa) Acids Transportation Polyunsaturated Fatty Acids |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Clinical Biochemistry |