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Ultrasound Strain Measurements for Evaluating Local Pulmonary Ventilation

Content Provider	Scilit
Author	Rubin, Jonathan M. Horowitz, Jeffrey C. Sisson, Thomas H. Kim, Kang Ortiz, Luis A. Hamilton, James D.
Copyright Year	2016
Description	Journal: Ultrasound in medicine & biology Local lung function is difficult to evaluate, because most lung function estimates are either global in nature (e.g., pulmonary function tests) or require equipment that cannot be used at a patient's bedside, such as computed tomography. Yet, local function measurements would be highly desirable for many reasons. Recently, we were able to track displacements of the lung surface during breathing. We have now extended these results to measuring lung strains during respiration as a means of assessing local lung ventilation. We studied two human volunteers and 14 mice with either normal lung function or experimentally induced pulmonary fibrosis. The differences in strains between the control, normal mice and those with pulmonary fibrosis were significant (p < 0.0001), whereas the strains measured in the human volunteers closely matched linear strains predicted from the literature. It may be possible to use ultrasonography to assess local lung ventilation in a clinical setting.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497456/pdf http://www.umbjournal.org/article/S0301562916301065/pdf
Ending Page	2531
Page Count	7
Starting Page	2525
ISSN	03015629
e-ISSN	1879291X
DOI	10.1016/j.ultrasmedbio.2016.05.020
Journal	Ultrasound in medicine & biology
Issue Number	11
Volume Number	42
Language	English
Publisher	Elsevier BV
Publisher Date	2016-08-10
Access Restriction	Open
Subject Keyword	Journal: Ultrasound in medicine & biology Respiratory System Ultrasound Strain Measurement Lung Ventilation Lung Ventilator Monitoring Pulmonary Fibrosis Lung Ultrasound Chronic Obstructive Pulmonary Disease Acute Respiratory Distress Syndrome
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Acoustics and Ultrasonics Biophysics Radiological and Ultrasound Technology

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