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A Community Effort to Protect Genomic Data Sharing, Collaboration and Outsourcing
| Content Provider | Scilit |
|---|---|
| Author | Wang, Shuang Jiang, Xiaoqian Tang, Haixu Wang, Xiaofeng Bu, Diyue Carey, Knox Dyke, Stephanie Om Fox, Dov Jiang, Chao Lauter, Kristin Malin, Bradley Sofia, Heidi Telenti, Amalio Wang, Lei Wang, Wenhao Ohno-Machado, Lucila |
| Copyright Year | 2017 |
| Description | Journal: SSRN Electronic Journal The human genome can reveal sensitive information and is potentially re-identifiable, which raises privacy and security concerns about sharing such data on wide scales. In 2016, we organized the third Critical Assessment of Data Privacy and Protection competition as a community effort to bring together biomedical informaticists, computer privacy and security researchers, and scholars in ethical, legal, and social implications (ELSI) to assess the latest advances on privacy-preserving techniques for protecting human genomic data. Teams were asked to develop novel protection methods for emerging genome privacy challenges in three scenarios: Track (1) data sharing through the Beacon service of the Global Alliance for Genomics and Health. Track (2) collaborative discovery of similar genomes between two institutions; and Track (3) data outsourcing to public cloud services. The latter two tracks represent continuing themes from our 2015 competition, while the former was new and a response to a recently established vulnerability. The winning strategy for Track 1 mitigated the privacy risk by hiding approximately 11% of the variation in the database while permitting around 160,000 queries, a significant improvement over the baseline. The winning strategies in Tracks 2 and 3 showed significant progress over the previous competition by achieving multiple orders of magnitude performance improvement in terms of computational runtime and memory requirements. The outcomes suggest that applying highly optimized privacy-preserving and secure computation techniques to safeguard genomic data sharing and analysis is useful. However, the results also indicate that further efforts are needed to refine these techniques into practical solutions. |
| Related Links | http://europepmc.org/articles/pmc5677972?pdf=render https://papers.ssrn.com/sol3/Delivery.cfm?abstractid=3157968 |
| ISSN | 10914358 |
| e-ISSN | 15565068 |
| DOI | 10.2139/ssrn.3157968 |
| Journal | SSRN Electronic Journal |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2017-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: SSRN Electronic Journal Medical Informatics Genomic Data Sharing Genome Informatics Genomic Analysis Human Genomic Data Privacy Genetic Diseases |
| Content Type | Text |
| Resource Type | Article |
| Subject | Public Health, Environmental and Occupational Health Psychiatry and Mental Health |
