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Optimizing operational efficiencies in early phase trials: The Pediatric Trials Network experience

Content Provider	Scilit
Author	Wade, Kelly Smith, P. Brian Berezny, Katherine Laughon, Matthew
Copyright Year	2016
Description	Journal: Contemporary Clinical Trials Performing drug trials in pediatrics is challenging. In support of the Best Pharmaceuticals for Children Act, the Eunice Kennedy Shriver National Institute of Child Health and Human Development funded the formation of the Pediatric Trials Network (PTN) in 2010. Since its inception, the PTN has developed strategies to increase both efficiency and safety of pediatric drug trials. Through use of innovative techniques such as sparse and scavenged blood sampling as well as opportunistic study design, participation in trials has grown. The PTN has also strived to improve consistency of adverse event reporting in neonatal drug trials through the development of a standardized adverse event table. We review how the PTN is optimizing operational efficiencies in pediatric drug trials to increase the safety of drugs in children.
Related Links	http://europepmc.org/articles/pmc4997801?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997801/pdf http://www.contemporaryclinicaltrials.com/article/S1551714416300283/pdf
Ending Page	382
Page Count	7
Starting Page	376
ISSN	15517144
DOI	10.1016/j.cct.2016.03.002
Journal	Contemporary Clinical Trials
Volume Number	47
Language	English
Publisher	Elsevier BV
Publisher Date	2016-03-08
Access Restriction	Open
Subject Keyword	Journal: Contemporary Clinical Trials Pediatrics and Child Health Best Pharmaceuticals for Children Act Eunice Kennedy Shriver National Institute of Child Health and Human Development Pediatric Trials Network Pediatric Drug Trials Adverse Events Organizational Improvements
Content Type	Text
Resource Type	Article
Subject	Pharmacology (medical)

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Optimizing operational efficiencies in early phase trials: The Pediatric Trials Network experience

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