A retrospective multicenter study of the natural history of fetal ovarian cysts

Content Provider	Scilit
Author	Tyraskis, Athanasios Bakalis, Spyros Scala, Carolina Syngelaki, Argyro Giuliani, Stefano Davenport, Mark David, Anna L. Nicolaides, Kypros Eaton, Simon Coppi, Paolo De
Copyright Year	2018
Description	Journal: Journal of pediatric surgery Aim We investigated the natural history of fetal ovarian cysts to estimate the risk of torsion according to size. Methods Cases were identified from 1/1/2000 until 1/1/2015. Data were collected pre- and postnatally on cyst size and sonographic features until an outcome of surgery, torsion, or resolution. Fisher's exact test for categorical data and logistic regression for continuous data were used to test the significance of size on torsion; P value <0.05 was considered significant. Results 37 patients with unilateral ovarian cysts were included. 12 (32%) resolved spontaneously prenatally, 14 (38%) resolved spontaneously postnatally, 5 (14%) underwent surgery postnatally and 6 (16%) cases underwent torsion. Rate of torsion increased with size from 0% (n=0) in cysts ≤20mm to 33% (n=2) in cysts >50mm; however, the overall trend failed to reach statistical significance (P=0.1). Cysts of 0–40mm had a significantly higher rate of spontaneous resolution (90% vs. 44% in >40mm, P=0.003), but the rate of torsion was not significantly different (10% in 0–40mm vs. 25% in >40mm, P=0.26). The median time to postnatal resolution was 10 (5–27) weeks in those treated conservatively. Conclusion Cysts >40mm are significantly less likely to resolve spontaneously; however torsion showed no significant correlation with cyst size. No complications were observed in cysts <20mm. Level of Evidence IV, case series with no comparison group.
Related Links	https://kclpure.kcl.ac.uk/portal/files/87226484/A_Retrospective_Multicenter_Study_TYRASKIS_Publishedonline12February2018_GREEN_AAM_CC_BY_NC_ND_.pdf http://www.jpedsurg.org/article/S0022346818301039/pdf
Ending Page	2022
Page Count	4
Starting Page	2019
ISSN	00223468
e-ISSN	15315037
DOI	10.1016/j.jpedsurg.2018.02.049
Journal	Journal of pediatric surgery
Issue Number	10
Volume Number	53
Language	English
Publisher	Elsevier BV
Publisher Date	2018-03-11
Access Restriction	Open
Subject Keyword	Journal: Journal of pediatric surgery Obstetrics and Gynecology Fetal Ovarian Cyst Ovarian Torsion Prenatal Diagnosis Prenatal Aspiration Fetal Intervention
Content Type	Text
Resource Type	Article
Subject	Surgery Pediatrics, Perinatology and Child Health