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Increasing diversion of methadone in Vancouver, Canada, 2005–2015
| Content Provider | Scilit |
|---|---|
| Author | Reddon, Hudson Ho, Joel DeBeck, Kora Milloy, M. -J. Liu, Yang Dong, Huiru Ahamad, Keith Wood, Evan Kerr, Thomas Hayashi, Kanna |
| Copyright Year | 2017 |
| Description | Journal: Journal of substance abuse treatment Background and aim Although methadone, an opioid agonist, has been an effective medication used to treat opioid use disorder for over 40years, recent studies have found that methadone was identified in more than a quarter of prescription opioid-related deaths among people who use illicit drugs in Vancouver, Canada. Thus, we sought to longitudinally examine the availability of diverted methadone among people who inject drugs (PWID). Design and methods Data were collected from three prospective cohorts of PWID in Vancouver, Canada between December 2005 and May 2015. Multivariable generalized estimating equation logistic regression was used to identify temporal trends in the immediate availability of diverted methadone (defined as the ability to acquire illicit methadone in <10min). Results A total of 2092 participants, including 727 (34.8%) women, were included in the present study. In the multivariable analyses after adjusting for a range of potential confounders, later calendar year (adjusted odds ratio [AOR]=1.21 per year; 95% confidence interval [CI]: 1.19–1.23) was independently and positively associated with reporting immediate availability of diverted methadone. Conclusions We observed a significant increase in the reported availability of diverted methadone among PWID over a ten-year follow-up period. Further research is needed to identify strategies to limit methadone diversion and assess the impact of alternative medications that are equally effective but safer, such as buprenorphine/naloxone. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753607/pdf http://www.journalofsubstanceabusetreatment.com/article/S0740547217302957/pdf |
| Ending Page | 16 |
| Page Count | 7 |
| Starting Page | 10 |
| ISSN | 07405472 |
| e-ISSN | 18736483 |
| DOI | 10.1016/j.jsat.2017.11.010 |
| Journal | Journal of substance abuse treatment |
| Volume Number | 85 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2017-11-28 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of substance abuse treatment Substance Abuse Illicit Drug Use |
| Content Type | Text |
| Resource Type | Article |
| Subject | Clinical Psychology Psychiatry and Mental Health |
