NDLI: Validation of a new multiscale finite element analysis approach at the distal radius

Please wait, while we are loading the content...

Validation of a new multiscale finite element analysis approach at the distal radius

Content Provider	Scilit
Author	Johnson, Joshua E. Troy, Karen L.
Copyright Year	2017
Description	Journal: Medical engineering & physics High-resolution peripheral computed tomography is commonly used to evaluate mechanical behavior of the distal radius microstructure using micro-finite element (FE) modeling. However, only a 9mm section is considered and boundary conditions (BCs) are usually simplified (platen-compression), and may not represent physiologic loading. Regardless, these methods are increasingly being used for clinical evaluations. Our goal was to develop and validate a novel multiscale solution that allows for physiologically relevant loading simulations (such as bracing during a fall), and show that mechanical behavior in the distal radius is different under platen BCs. Our approach incorporated bone microstructure together with organ-level radius geometry, by replacing matching continuum regions with micro-FE sections in user-defined regions of interest. Multiscale model predicted strains showed a strong correlation and a significant relationship with measured strains (r=0.836, p<0.001; slope=0.881, intercept=-12.17 µε, p<0.001). Interestingly, platen BC simulated strains were almost 50% lower than measured strains (r=0.835, p<0.001), and strain distributions were clearly different. Our multiscale method demonstrated excellent potential as a computationally efficient alternative for observing true mechanical environment within distal radius microstructure under physiologically accurate loading.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415424/pdf
Ending Page	24
Page Count	9
Starting Page	16
ISSN	13504533
e-ISSN	18734030
DOI	10.1016/j.medengphy.2017.03.005
Journal	Medical engineering & physics
Volume Number	44
Language	English
Publisher	Elsevier BV
Publisher Date	2017-06-01
Access Restriction	Open
Subject Keyword	Journal: Medical engineering & physics Continuum Finite Element High-resolution Peripheral Computed Tomography Micro-finite Element
Content Type	Text
Resource Type	Article
Subject	Biophysics Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius

Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 2002;30:842–8.

A Local Adaptive Threshold Strategy for High Resolution Peripheral Quantitative Computed Tomography of Trabecular Bone

Simplified boundary conditions alter cortical-trabecular load sharing at the distal radius; A multiscale finite element analysis

High-Resolution peripheral Quantitative Computed Tomography Based Finite Element Modelling of Distal Radius Strength: Assessing Effect of Heterogeneous Material Properties and Scan Site

Validation of distal radius failure load predictions by homogenized- and micro-finite element analyses based on second-generation high-resolution peripheral quantitative CT images

Bone Microarchitecture and Distal Radius Fracture Pattern Complexity

Composite time-lapse computed tomography and micro finite element simulations: A new imaging approach for characterizing cement flows and mechanical benefits of vertebroplasty.

Bone density, geometry, microstructure, and stiffness: Relationships between peripheral and central skeletal sites assessed by DXA, HR-pQCT, and cQCT in premenopausal women

Validation of a new multiscale finite element analysis approach at the distal radius

Similar Documents

Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius

Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 2002;30:842–8.

A Local Adaptive Threshold Strategy for High Resolution Peripheral Quantitative Computed Tomography of Trabecular Bone

Simplified boundary conditions alter cortical-trabecular load sharing at the distal radius; A multiscale finite element analysis

High-Resolution peripheral Quantitative Computed Tomography Based Finite Element Modelling of Distal Radius Strength: Assessing Effect of Heterogeneous Material Properties and Scan Site

Validation of distal radius failure load predictions by homogenized- and micro-finite element analyses based on second-generation high-resolution peripheral quantitative CT images

Bone Microarchitecture and Distal Radius Fracture Pattern Complexity

Composite time-lapse computed tomography and micro finite element simulations: A new imaging approach for characterizing cement flows and mechanical benefits of vertebroplasty.

Bone density, geometry, microstructure, and stiffness: Relationships between peripheral and central skeletal sites assessed by DXA, HR-pQCT, and cQCT in premenopausal women

Validation of a new multiscale finite element analysis approach at the distal radius