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A revised model for estimating g-ratio from MRI
| Content Provider | Scilit |
|---|---|
| Author | West, Kathryn L. Kelm, Nathaniel D. Carson, Robert P. Does, Mark D. |
| Copyright Year | 2016 |
| Description | Journal: Neuroimage A key measure of white matter health is the g-ratio, which is defined as the ratio between the inner axon radius and the outer, myelinated, axon radius. Recent methods have been proposed to measure the g-ratio non-invasively using the relationship between two magnetic resonance imaging (MRI) measures. While this relationship is intuitive, it predicates on the simplifying assumption that g-ratio is constant across axons. Here, we extend the model to account for a distribution of g-ratio values within an imaging voxel, and evaluate this model with quantitative histology from normal and hypomyelinated mouse brains. |
| Related Links | http://europepmc.org/articles/pmc4691384?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691384/pdf |
| Ending Page | 1158 |
| Page Count | 4 |
| Starting Page | 1155 |
| ISSN | 10538119 |
| DOI | 10.1016/j.neuroimage.2015.08.017 |
| Journal | Neuroimage |
| Volume Number | 125 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2016-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Neuroimage Magnetic Resonance Imaging |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Cognitive Neuroscience |