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Prevalence and Severity of Nonalcoholic Fatty Liver Disease Among Caregivers of Patients With Nonalcoholic Fatty Liver Disease Cirrhosis
| Content Provider | Scilit |
|---|---|
| Author | Siddiqui, Mohammad Shadab Carbone, Salvatore Vincent, Robert Patel, Samarth Driscoll, Carolyn Celi, Francesco S. Billingsley, Hayley Rotelli, Brando John, Binu Potere, Nicola Viscusi, Michele Adiletta, Veronica Sanyal, Arun J. Luketic, Velimir A. Reichman, Trevor Bhati, Chandra S. |
| Copyright Year | 2018 |
| Description | Journal: Clinical Gastroenterology and Hepatology Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, affecting nearly 1 in 3 Americans.1 Nonalcoholic steatohepatitis (NASH), the clinically aggressive variant of NAFLD, has a propensity of fibrosis progression and increased risk of cirrhosis and hepatocellular carcinoma. NASH-related cirrhosis is now the most rapidly growing indication for liver transplantation (LT).2 Disease recurrence and progression to advanced fibrosis after LT are high3; however, the key contributors of these are unknown. We hypothesized that patients with NASH cirrhosis reside in a microenvironment conducive to not only development of NASH but also fibrosis progression, which likely persist after LT and contribute to disease recurrence. The hypothesis was tested by performing vibration-controlled transient elastography (VCTE) in primary caregivers and cohabitants of patients with decompensated cirrhosis awaiting LT. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018437/pdf http://www.cghjournal.org/article/S1542356518312515/pdf |
| Ending Page | 2133 |
| Page Count | 2 |
| Starting Page | 2132 |
| ISSN | 15423565 |
| e-ISSN | 15427714 |
| DOI | 10.1016/j.cgh.2018.11.008 |
| Journal | Clinical Gastroenterology and Hepatology |
| Issue Number | 10 |
| Volume Number | 17 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2018-11-15 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinical Gastroenterology and Hepatology Controlled Attenuation Parameter Liver Stiffness Measurement Liver Transplantation Nonalcoholic Fatty Liver Disease Nonalcoholic Steatohepatitis Vibration-controlled Transient Elastography |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hepatology Gastroenterology |
