Loading...
Please wait, while we are loading the content...
Similar Documents
First-in-human imaging using a MR-compatible e4D ultrasound probe for motion management of radiotherapy
| Content Provider | Scilit |
|---|---|
| Author | Bednarz, Bryan P. Jupitz, Sydney Lee, Warren Mills, David Chan, Heather Fiorillo, Timothy Sabitini, James Shoudy, David Patel, Aqsa Mitra, Jhimli Sarcar, Shourya Wang, Bo Shepard, Andrew Matrosic, Charles Holmes, James Culberson, Wesley Bassetti, Michael Hill, Patrick McMillan, Alan Zagzebski, James Smith, L. Scott Foo, Thomas K. |
| Copyright Year | 2021 |
| Description | Journal: Physica Medica Purpose Respiration-induced tumor or organ positional changes can impact the accuracy of external beam radiotherapy. Motion management strategies are used to account for these changes during treatment. The authors report on the development, testing, and first-in-human evaluation of an electronic 4D (e4D) MR-compatible ultrasound probe that was designed for hands-free operation in a MR and linear accelerator (LINAC) environment. Methods Ultrasound components were evaluated for MR compatibility. Electromagnetic interference (EMI) shielding was used to enclose the entire probe and a factory-fabricated cable shielded with copper braids was integrated into the probe. A series of simultaneous ultrasound and MR scans were acquired and analyzed in five healthy volunteers. Results The ultrasound probe led to minor susceptibility artifacts in the MR images immediately proximal to the ultrasound probe at a depth of <10 mm. Ultrasound and MR-based motion traces that were derived by tracking the salient motion of endogenous target structures in the superior-inferior (SI) direction demonstrated good concordance (Pearson correlation coefficients of 0.95–0.98) between the ultrasound and MRI datasets. Conclusion We have demonstrated that our hands-free, e4D probe can acquire ultrasound images during a MR acquisition at frame rates of approximately 4 frames per second (fps) without impacting either the MR or ultrasound image quality. This use of this technology for interventional procedures (e.g. biopsies and drug delivery) and motion compensation during imaging are also being explored. |
| Related Links | http://www.physicamedica.com/article/S1120179721002404/pdf |
| Ending Page | 110 |
| Page Count | 7 |
| Starting Page | 104 |
| ISSN | 11201797 |
| DOI | 10.1016/j.ejmp.2021.06.017 |
| Journal | Physica Medica |
| Volume Number | 88 |
| Language | English |
| Publisher | Elsevier BV |
| Publisher Date | 2021-07-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Physica Medica Radiology, Nuclear Medicine and Imaging Motion Management |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Physics and Astronomy Biophysics |
